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HostsManager can easily change your host.

You can create application profiles with rooSwitch Lite

Family can create family trees in the most intuitive way.

NTFS-3G can read-write NTFS filesystem driver.

You can create encrypted volumes with OSXCrypt.

EPSQLPlugIn can display previews of EPS files.

You can connect your Newton device to your Mac with Newton Connection.

Stronghold can keeps data safe under 448-bit blowfish encryption.

You can adds functionality to iWeb with iTweak.

Netrix is a free tetris clone which you can play in either single or multiplayer